O13.4 Cervicovaginal microbiome dysbiosis is associated with proteome changes related to alterations of the cervicovaginal mucosal barrier
نویسندگان
چکیده
منابع مشابه
In Captive Rhesus Macaques, Cervicovaginal Inflammation Is Common but Not Associated with the Stable Polymicrobial Microbiome
Vaginal inoculation of rhesus macaques (RM) with simian immunodeficiency virus (SIV) has been used to study the biology of HIV transmission. Although the results of vaginal SIV transmission experiments could be affected by vaginal inflammation, studies to date have been conducted without regard to levels of pre-existing genital inflammation present in RM. We collected cevicovaginal secretions (...
متن کاملRole of Lactobacilli and Lactoferrin in the Mucosal Cervicovaginal Defense
The innate defense system of the female mucosal genital tract involves a close and complex interaction among the healthy vaginal microbiota, different cells, and various proteins that protect the host from pathogens. Vaginal lactobacilli and lactoferrin represent two essential actors in the vaginal environment. Lactobacilli represent the dominant bacterial species able to prevent facultative an...
متن کاملMucosal microbiome dysbiosis in gastric carcinogenesis.
OBJECTIVES We aimed to characterise the microbial changes associated with histological stages of gastric tumourigenesis. DESIGN We performed 16S rRNA gene analysis of gastric mucosal samples from 81 cases including superficial gastritis (SG), atrophic gastritis (AG), intestinal metaplasia (IM) and gastric cancer (GC) from Xi'an, China, to determine mucosal microbiome dysbiosis across stages o...
متن کاملReport of surgical correction of a cervicovaginal agenesis case: cervicovaginal reconstruction with pudendal thigh flaps
Congenital agenesis of the uterine cervix and vagina in the presence of a functional endometrium is an extremely rare mullerian anomaly [1]. Congenital vaginal agenesis occurs with a prevalence of 1/4000-1/5000 live-born females, while the accurate incidence of cervicovaginal agenesis is controversial [1-3]. Cervicovaginal agenesis is usually not diagnosed until menarche. It is manifested by th...
متن کاملBiliary Mucosal Barrier and Microbiome
BACKGROUND The biliary system is in continuous contact with the complex microbiota of the intestine. Microbial products have recently been proposed as potential triggers for biliary diseases. METHODS The aim of this review is to provide a summary of the current knowledge regarding the role of the biliary and intestinal microbiome in biliary inflammatory diseases. RESULTS Previously, it was ...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 2015
ISSN: 1368-4973,1472-3263
DOI: 10.1136/sextrans-2015-052270.150